A:
MEPIVACAINE HYDROCHLORIDE 3% WITHOUT VASOCONSTRICTOR (EPINEPHRINE)
MANUFACTURER: COOK-WAITE BY NOVOCOL PHARMACEUTICAL OF CANADA, INC
BRAND NAME: CARBOCAINE
Date: April 22, 2025
Is there graphene, graphene oxide, graphene hydroxide, cadmium, PEG 2000, PEG 5000, cesium 137, cesium chloride, or other related particles in dental anesthetic?
We asked the University of Colorado Boulder to test samples of dental anesthetic. We sent samples of Carbocaine (Mepivacaine Hydrochloride 3%), lot # (10) D04578G, with expiration 04/30/2026. At the conclusion of testing, Jessica C. Hankins, Facility Manager and Research Scientist in the Raman Microspectroscopy Lab reports:
“Carbon Complexes: Several spectra exhibit broad D and G bands (~1350 cm-1 and ~1585 cm-1, respectively), consistent with disordered sp2-hybridized carbon. One spectrum also displays a broad, low-intensity feature in the ~2700 cm-1 range that may represent a weak 2D band, however, the remaining spectra lack a discernible 2D feature. Although some studies have identified materials as graphene oxide in the absence of resolved 2D band, its structural heterogeneity inhibits confident classification by Raman spectroscopy alone.
Unknown compounds: These spectra do not exhibit peaks representative of graphene oxide or related carbon structures. Spectrum were unable to be successfully identified due to a lack of available reference databases in our system and are included solely for documentation purposes.
Identified spectra: Three spectra yielded tentative matches to common mineral species via database comparison:
· Magnetite (Fe3O4): An iron oxide mineral frequently found in natural and industrial dust
· Quartz (SiO2): A ubiquitous silicate mineral present in terrestrial environments and ambient airborne particulates
· Serpentine-group phyllosilicate (best HQI match: chrysotile): While the spectrum aligned most closely with chrysotile, significant spectral overlap among serpentine minerals (e.g., lizardite, antigorite, chrysotile) limits the specificity of this particular match.
These mineral phases are frequently encountered as trace constituents in environmental dust and airborne particulates. Their presence in this analysis is likely incidental and does not suggest functional relevance to the anesthetic formulation.”
You can view the full report here:
Date: February 5, 2025
Is there SV40 (Pfizer) qPCR, SV40 (Pfizer) RT-qPCR (RNA), Spike (Pfizer, Moderna, J&J, AZ) RT-qPCR (RNA), Ori (Pfizer & Moderna) qPCR, Ori (Pfizer & Moderna) RT-qPCR (RNA), TAC (16S-Bacterial) qPCR, TYM (ITS-Fungal) qPCR, Brewer’s Yeast gene 1616, Marburg Virus, or Mpox in dental anesthetic?
We asked Kevin McKernan with Medicinal Genomics to test samples of dental anesthetic. The testing was completed on Carbocaine (Mepivacaine Hydrochloride), lot # (10) D04578G with expiration date 04/30/2026. At the conclusion of testing, negative results were reported on all tests completed.
You can view the full report here:
ARTICAINE HYDROCHLORIDE 4% AND EPINEPHRINE 1:200,000
MANUFACTURER: SEPTODONT BY NOVOCOL PHARMACEUTICAL OF CANADA, INC
BRAND NAME: SEPTOCAINE
Date: December 4, 2024
Is there graphene, graphene oxide, graphene hydroxide or other related particles in dental anesthetic?
We asked the University of Colorado Boulder to test samples of dental anesthetic. We sent samples of Septocaine (Articaine Hydrochloride 4% and Epinephrine 1:200,000), lot # (10) D04530B, with expiration date 02/28/2026. At the conclusion of testing, Jessica C. Hankins, Sr Professional Research Assistant, Raman Microspectroscopy and Geomicrobiology Lab Manager reports: "Carbon Complexes: Denoted peak positions correlate to the D and G peaks of graphene oxide (~1350cm-1 and ~1585 cm-1 respectively), but there is no 2D peak in the ~2700 cm-1 range. A material can be categorized as graphene oxide with the absence of the 2D peak, however, I cannot say with certainty that these particles are composed of graphene oxide from this analysis alone."
You can view the full report here:
Date: August 21, 2024
Are there nanoparticles in dental anesthetic?
We asked NanoImaging Services to perform cryo transmission electron microscopy (cryoTEM) imaging on dental anesthetic samples. The imaging was completed on Septocaine (Articaine Hydrochloride 4% and Epinephrine 1:200,000), lot # (10) D04530B, with expiration date 02/28/2026. At the completion of testing, NIS reports: "The cryoTEM images of Septocaine, Aliquot 1 did not contain any distinct lipid nanoparticles, carbon structures, or other nanoparticles; note that any low number of particles that are smaller than ~5 nm in size will not be visible in the images. The images showed some degree of ice contamination (black particles), which is not unusual for vitrified samples."
You can view the full report here:
Date: August 20, 2024
Is there RNA, DNA, bacteria or fungus in dental anesthetic?
We asked Kevin McKernan with Medicinal Genomics to test samples of dental anesthetic. The testing was completed on Septocaine (Articaine Hydrochloride 4% and Epinephrine 1:200,000), lot # (10) D04530B, with expiration date 02/28/2026. At the conclusion of testing, negative results were reported on all tests completed.
You can view the full report here:
ARTICAINE HYDROCHLORIDE 4% AND EPINEPHRINE 1:200,000
MANUFACTURER: PIERREL
BRAND NAME: ORABLOC
Date: July 22, 2024
Is there Graphene in dental anesthetic?
We asked the University of Colorado Boulder to test samples of dental anesthetic. We sent samples of Articaine Hydrochloride 4% and epinephrine 1:200,000, lot number (10) 230109 for testing. The testing was completed using Raman Microspectroscopy. At the conclusion of testing, Jessica C. Hankins, Sr Professional Research Assistant, Raman Microspectroscopy and Geomicrobiology Lab Manager reports "I can affirm the presence of graphene oxide particles in this anesthetic with high confidence."
You can view the full report here:
Date: September 28, 2023
Is there RNA or DNA in dental anesthetic?
We asked Kevin McKernan with Medicinal Genomics to test samples of dental anesthetic. The testing was completed on Articaine Hydrochloride 4% and epinephrine 1:200,000, lot number (10) 230109. At the conclusion of testing, he reports no detectable vaccine derived RNA or DNA is present in the anesthetic.
You can view the full report here:
Date: August 9, 2023
Preliminary testing results from Dr. Ana Maria Mihalcea
Dr. Ana Maria Mihalcea was first to respond to our request for testing the lot of dental anesthetic. She completed her testing on Articaine Hydrochloride 4% and epinephrine 1:200,00, lot number (10) 230109 using Dark Field Microscopy. Her preliminary results are partially available on her substack @anamihalceamdphd and you can also view the substack article below.
You can view the report here:
