We have been receiving questions from our patients regarding our injectable products. For example, does our anesthetic contain graphene, graphene oxide, graphene hydroxide or the technology (not perhaps an ingredient) that would be termed lipid nanoparticles or hydrogel. We believe the real question is do our injectable products contain an ingredient, technology or a payload that is not needed for the function of the product itself. In an effort to answer these questions for our patients, we have asked the manufacturers of our injectable products to state specific answers to these questions on official company letterhead. With the help of the IAOMT (International Academy of Oral Medicine and Toxicology) we are also pursuing testing of dental anesthetics.
We will continue to post information on this page as we receive it. If you would like to reach out to Dr. Lundstrom with questions, you can reach him via email at lundstrommanager@protonmail.com.
How can dental anesthetic be tested?
We began the process of getting answers on the safety of dental anesthetic in February 2023. We began by contacting the manufacturers of the anesthetic and in July 2023 Dr. Lundstrom partnered with the IAOMT to pursue testing of the anesthetic. Our hope was that with the weight of the IAOMT and their 1520 members we would accomplish our goal of getting the anesthetic tested and answering the question of dental anesthetic safety.
Who has completed testing on the dental anesthetic?
Dr. Ana Maria Mihalcea
She completed testing using Dark Field Microscopy. Her preliminary results are posted below in our August 9, 2023 update.
Kevin McKernan
He completed testing using Genomic Sequencing. His results are posted below in our September 28, 2023 update.
What dental anesthetic has been tested?
Articaine Hydrochloride 4% and epinephrine 1:200,000
Manufacturer: Pierrel
Brand Name: Orabloc
Who have we contacted about testing the dental anesthetic?
We have reached out to many sources to inquire about getting testing completed either through them/their universities or asking them to provide us with contacts for a trusted testing site. Along with asking for testing to be completed, we have also provided some of the sources with samples of dental anesthetic for testing. Below you will see the efforts we have made in trying to pursue testing and some of the responses we have received.
Dr. Gossweiler, DDS, NMD, IAOMT Science Committee Member
August 9, 2023 we provided a sample of dental anesthetic for testing but haven't received confirmation that testing will be completed.
Jacob Erstling, PhD, Cornell Alum, Director of Internal Production at Eulicida Oncology, Inc
December 20, 2023 we provided a sample of dental anesthetic for testing. We also inquired about how someone could detect the presence of C'Dots or related nanotechnology and what testing methods could be used for this. No response has been received.
Ulrich Wiesner, Cornell University Spencer T. Olin Professor in the Department of Materials Science and Engineering
December 20, 2023 we provided a sample of dental anesthetic for testing. We also inquired about how someone could detect the presence of C'Dots or related nanotechnology and what testing methods could be used for this. No response has been received.
The University of Utah, Utah Nanofab
The University of Utah website states: Utah Nanofab has become a world leader in the fabrication of neural prosthetics, biomedical microfluidic systems and biosensor chips. Utah Nanofab has the specialized custom-built infrastructure, equipment, processes, and expertise necessary for researchers and companies to design, build, and package revolutionary micro and nanoscale devices.
Paulo Perez, The University of Utah, Utah Nanofab, University Surface Scientist
November 30, 2023 we provided a sample of dental anesthetic for testing. No response has been received.
Brian Van Devener, The University of Utah, Utah Nanofab Surface Analysis Lab Manager, University Surface Scientist
November 30, 2023 we provided a sample of dental anesthetic for testing.
December 19, 2023 received response stating "Upon reviewing your request, this looks like something that is beyond the scope of our normal capabilities."
Stew Peters
No response received
Truth for Health Foundation
June 27, 2023 receipt of information confirmed but no response on testing
Todd Callender, Attorney at Disabled Rights Advocates
No response received
Mike Adams "The Health Ranger", Lab Science Director of CWC (Consumer Wellness Center) Labs
No response received
Dr. Richard Fleming, PhD, MD, SD, Creator of The Fleming Method
July 27, 2023 responded with potential testing methods but did not complete testing
FLCCC (Front Line Covid-19 Critical Care Alliance)
July 29, 2023 responded stating "We are a small non-profit that may seem very large because of our outreach, but we just don't have the resources or the funds to help with this. Once the data is gathered and there is evidence to prove that this is truly an issue of concern, then we can explore this further to see if we can make a difference through educating patients, consumers, and the anesthesia community on the risks of preservatives in local anesthesia. "They also made suggestions on how to collect data regarding dental anesthetic.
Tom Renz, Attorney
No response received
TrialSiteNews
No response received
Dr. Joseph Mercola, Osteopathic Physician, Founder and Owner of Mercola.com
No response received
ICAN (Informed Consent Action Network)
July 25, 2023 responded stating "We will forward this to our team and if we have further questions, we will be in touch with you. We are honored to hear your ideas and for you to reach out to us. It is this kind of collaboration that moves us forward."
Dr. Pablo Campra, PhD in Chemical Sciences at University of Almeria, Biological Science Graduate at University of Granada, Professor of the Agronomy Department at University of Almeria in Spain
February 6, 2024 responded stating "At the moment I am not authorized by my university to do such a job. But I recommend you to search for any university near you and call to Technical Services or just google where they offer micro-Raman service. Just Raman will not detect graphene if it is present in dispersed nanoparticles, and must be observed analyzed one by one. You can check the technique here. https://www.researchgate.net/publication/355979001_DETECTION_OF_GRAPHENE_IN_COVID19_VACCINES"
Dr. Ricardo Delgado Martin
No response received
Strategic Response Partners
No response received
Colleen Fitzgerald, NDSU Research and Creative Activity
January 3, 2024 responded stating "We don't currently have a Raman-Mass Spectrometer in our instrument portfolio. After careful consideration of your project, we have determined that the scope of the nanotechnology and number of possible contaminants would be challenging for our instrumentation and staff to provide reliable results."
Dr. Peter McCullough, MD, MPH
No response received
Dr. Diana Wojtkowiak
January 25, 2024 responded stating "Unfortunately, I don't have any specific leads, whether for an institution that would perform the tests or for the equipment. Two years ago, I was looking for classic methods of studying the presence of graphene in scientific publications and what information they provide. Raman microspectroscopy has proven to be the only useful method for treating small amounts of graphene that are introduced into single doses of drugs. It makes it possible to recognize the modification, whether it is an oxidized or reduced form, or even the presence of a curvature of the single-layer graphene layer itself. In this method, the laser beam is directed by the operator through the objective to the graphene flake visible under the microscope, and the reflected light is analyzed by infrared spectroscope. Since this method uses only the reflected radiation that has increased its energy, only one photon per million is used. This places very high demands on the optics of the spectroscope to pick out a small amount of photons with increased energy from the noise. The second potentially applicable method is electron paramagnetic resonance. However, this method requires a few milligrams of separated and dry graphene. So it's not useful here."
Applied Consumer Services, Inc.
January 25, 2024 we provided a sample of anesthetic and inquired about what testing method would be most appropriate to determine the ingredients in the anesthetic, potentially Deformulation.
Dr. Phillip Buckhaults, Ph.D., University of South Carolina, Drug and Discovery and Biomedical Sciences (DDBS) College of Pharmacy
No response received
John Kouvetakis, Arizona State University School of Molecular Sciences
No response received
Stuart Lindsay, Arizona State University, Center Director and Professor Biodesign Center for Single Molecule Biophysics, Regents Professor School of Molecular Sciences, Regents Professor Department of Physics, University Professor Biosocial Complexity Initiative, University Professor ASU SFI Center, University Professor Center for Biological Physics, University Professor ASU-SFI Fellow
February 6, 2024 responded stating "I was very surprised to hear about the possibility of graphene in dental anesthetics. A very recent research paper (J.Molecular Liquids vol 366 p120301 2022) has explored the use of graphene to extend the release time of small molecule anesthetics in theoretical study. I am not aware of any experimental studies. Graphene does have some distinct features in a Raman spectrum, but I doubt you'd see them in any solution not made black by the presence of graphene. Given this timescale, I think it inconceivable that the FDA would have permitted this. The simple solution is to ask the manufacturer to state that graphene is NOT in the solution."
Nicholas Stephanopoulos, Arizona State University, Associate Professor School of Molecular Sciences, Associate Professor Sustainable Macromolecular Materials and Manufacturing Associate Faculty, Associate Director and Assistant Professor Biodesign Center for Molecular Design and Biomimetics
No response received
Is the tested dental anesthetic being used for patient care?
The lot of anesthetic that Dr. Lundstrom purchased is currently being used in our practice for patient care. We will continue to seek additional testing on this lot of anesthetic and will update our website accordingly as we receive results.
The Articaine (Orabloc) is the primary anesthetic we are currently using. If you are interested in a different anesthetic for your care we do have several other options available including Xylocaine, Citanest, Carbocaine, Septocaine, and more. Please feel free to reach out to us to discuss available anesthetic options or talk with your provider during your dental visit.
How can someone offer to test the dental anesthetic?
If you or anyone you know are willing to test the dental anesthetic please reach out to our office. We will provide a sample of anesthetic for testing purposes. You can contact us at lundstrommanager@protonmail.com to inquire about receiving samples.
Date: September 28, 2023
Is there RNA or DNA in dental anesthetic?
We asked Kevin McKernan with Medicinal Genomics to test samples of dental anesthetic. We sent him the same type of anesthetic and lot number that was tested by Dr. Ana Maria Mihalcea. The testing was completed on Articaine Hydrochloride 4% and epinephrine 1:200,000. At the conclusion of testing, he reports no detectable vaccine derived RNA or DNA is present in the anesthetic.
You can view the full report here:
Date: August 9, 2023
Update from Dr. Lundstrom
I am helping the IAOMT to establish a testing protocol for dental injectables. The goal is to make available tested lots of dental injectables to dental professionals. On behalf of the IAOMT, I have sent out letters asking for help on testing one lot of dental anesthetic. One lot of anesthetic represents over 25,000 carpules.
Dr. Ana Maria Mihalcea was first to respond to our request for testing the lot of dental anesthetic. Thank you to Dr. Mihalcea for being so responsive and promptly testing the anesthetic I sent. Dr. Mihalcea has preliminary results of her testing through Dark Field Microscopy. She completed testing on Articaine Hydrochloride 4% and epinephrine 1:200,000. Her preliminary results are partially available on her substack @anamihalceamdphd. I imagine she will post her final results on her substack as well.
Articaine Hydrochloride 4% with EPI 1:200,000
Manufacturer: Pierrel
Date: February 20, 2023
Is there any graphene, graphene hydroxide, graphene oxide, carbon nanoparticles, hydrogel or lipid nanoparticles added to your Articaine Hydrochloric 4% Local Anesthetic?
Date: February 23, 2023
Date: February 27, 2023
Date: October 12, 2023
Updated letter sent to Pierrel
Date: October 18, 2023
Prilocaine Hydrochloride 4% with EPI 1:200,000
Manufacturer: DentsplySirona
Date: February 20, 2023
Is there any graphene, graphene hydroxide, graphene oxide, carbon nanoparticles, hydrogel or lipid nanoparticles added to your Citanest Plain dental anesthetic?
Date: April 10, 2023
DentsplySirona was contacted through our distribution representative asking the following questions:
1. Did you add anything to the injectable product that is not needed for its function?
2. Does the injectable product contain graphene?
3. Does the injectable product contain graphene oxide?
4. Does the injectable product contain graphene hydroxide?
5. Does the injectable product contain lipid nanoparticle technology? (the technology which can be used to deliver a payload to the cells of the body, not necessarily considered an ingredient)
6. Does the injectable product contain a hydrogel technology? (might not by considered an ingredient)
7. Does the injectable product contain a technology, payload or ingredient that is not needed for its function?
8. Does the manufacturer have a contract or agreement with a third party to include a technology, payload or ingredient that is not needed for the injectable product?
Date: September 28, 2023
As of the date this web page was published, we have received no response from DentsplySirona regarding our questions. We will update the page if we receive correspondence from them.
Date: October 12, 2023
Updated letter sent to DentsplySirona
Carbocaine 3%
Manufacturer: Septodont
Date: February 21, 2023
Is there any graphene, graphene hydroxide, graphene oxide, carbon nanoparticles, hydrogel or lipid nanoparticles added to your Carbocaine Local Anesthetic?
Date: September 28, 2023
As of the date this web page was published, we have received no response from Septodont regarding our questions. We will update the page if we receive correspondence from them.
Date: October 12, 2023
Updated letter sent to Septodont
Lidocaine HCI 2% with EPI 1:100,000
Manufacturer: Septodont
Date: February 20, 2023
Is there any graphene, graphene hydroxide, graphene oxide, carbon nanoparticles, hydrogel or lipid nanoparticles added to your Lidocaine 2% Local Anesthetic?
Date: October 12, 2023
Updated letter sent to Septodont
OnSet
Manufacturer: OnPharma
Date: March 28, 2023
OnPharma was contacted through our distribution representative asking the following questions:
1. Did you add anything to the injectable product that is not needed for its function?
2. Does the injectable product contain graphene?
3. Does the injectable product contain graphene oxide?
4. Does the injectable product contain graphene hydroxide?
5. Does the injectable product contain lipid nanoparticle technology? (the technology which can be used to deliver a payload to the cells of the body, not necessarily considered an ingredient)
6. Does the injectable product contain a hydrogel technology? (might not be considered an ingredient)
7. Does the injectable product contain a technology, payload or ingredient that is not needed for its function?
8. Does the manufacturer have a contract or agreement with a third party to include a technology, payload or ingredient that is not needed for the injectable product?
Date: April 4, 2023
